Iterion Therapeutics

Founded in 2014, Iterion Therapeutics is a venture-backed, clinical-stage biotechnology company developing novel cancer therapeutics. The company's lead product, Tegavivint, is a potent and selective inhibitor of nuclear β-catenin, an oncology target implicated in cell proliferation, differentiation, immune evasion, and stem cell renewal. Iterion is also pursuing development in additional cancers where nuclear β-catenin signaling has been shown to play a role, including acute myeloid leukemia (AML), non-small cell lung cancer (NSCLC), and pediatric cancers, including sarcomas, lymphoma, and other solid tumors. The company is headquartered in Houston, Texas.