Leukemia Therapeutics

Leukemia Therapeutics aims to disrupt the leukemia drug market by introducing targeted antibody therapeutics that not only improve survival but also quality of life. The targets for therapeutic antibodies are discovered on the surface of leukemia by application of a validated proprietary platform. The therapeutic efficacy of engaging these targets with antibodies is tested in vivo using xenograft mouse models. In subsequent stages of development, humanized versions of the antibodies proven effective in xenograft models are generated, then validated in phase I and phase II clinical trials. Validated humanized antibodies are licensed through leverage of the open innovation business model recently adopted by the pharmaceutical industry. Currently, Leukemia Therapeutics has 5 lead therapeutic antibodies in development. Three of these represent novel treatments for adult T cell leukemia and two target hairy cell leukemia. Novel targets for the treatment of acute myeloid leukemia are in the discovery phase of the product pipeline.